Prokaryotic Glycoproteins: Unexplored but Important

GUEST COMMENTARIES Prokaryotic Glycoproteins: Unexplored but Important

ProGlycProt: a repository of experimentally characterized prokaryotic glycoproteins

ProGlycProt (http://www.proglycprot.org/) is an open access, manually curated, comprehensive repository of bacterial and archaeal glycoproteins with at least one experimentally validated glycosite (glycosylated residue). To facilitate maximum information at one point, the database is arranged under two sections: (i) ProCGP-the main data section consisting of 95 entries with experimentally chara...

Respiratory disease, the environment, and the military: important, unexplored frontiers.

In this issue of the Journal, Broderick et al. [1] report on the incidence of febrile respiratory illness (FRI) among Marine recruits during their first 4 weeks of military training, as well as the effect that closed training environments (units closed to the influx of potentially infectious convalescing persons [hereafter referred to as “closed units”]) versus open training environments (units...

The adsorption of biological peptides and proteins at the oil/water interface. A potentially important but largely unexplored field.

This review focuses on some new techniques to study the behavior of peptides and proteins bound to oil droplets. We will show how model peptides e.g., amphipathic alpha helices (AalphaH) and amphipathic beta strand (AbetaS) and some apolipoproteins adsorb to triacylglycerol (TAG) droplets and how they behave once adsorbed to the interface. While most of the studies described involve peptides an...

Not significant but important.

Armstrong and colleagues report the result of a large Phase IIb randomized trial evaluating the effectiveness of a preparation of the Bowman Birk Inhibitor compared with an oral placebo in reversing the extent of oral leukoplakia as measured visually by pathology or a battery of intermediate end points. In this editorial, we review the report of this negative clinical trials result to highlight...